We have already discussed the situation, when there is a chance to get off the pressure pills. Now it's a different story. Let's say the person didn't have a chance, but they show off and quit anyway.
There are four ways:
- This weirdo will not feel anything and will live as before. True, his pressure will very quickly become as high as before.
- The pressure will become as high as before, but not instantly, but over a period of time.
- Withdrawal will begin with a sharp activation of the nervous system. This is called withdrawal syndrome.
- The pressure will not just return to the previous level, but will go off scale even higher than it was.
The second option is most often encountered. The pressure will gradually rise. This can take days, weeks, or even up to six months. Somewhere among these people there will be those lucky ones who managed to refuse drugs with impunity. Even after a year, their blood pressure will remain normal.
If people from this group are properly scared and forced to lose weight, limit salt and drive them out for a walk with Nordic walking, then the percentage of lucky ones among them will increase.
Withdrawal syndrome
The most brutal withdrawal syndrome will be from clonidine. It acts on receptors in the brain, and after a sharp withdrawal, a real withdrawal begins with a jump in pressure, agitation, headache, nausea, and shaking hands.
Beta-blockers are also not always able to be abolished with impunity, because they block adrenaline in a peaceful life. Well, after the cancellation, adrenaline shows all those bad qualities for which adrenaline has always been famous. The effect of adrenaline on the heart and blood vessels can be something like a bear chasing you.
The severity of this withdrawal syndrome depends on the duration of the drug's action and on the number of receptors on which the drug acts.
That is, if a person was fed at least a week with beta-blockers, then during this time his body (he is not a fool) already understands that some kind of hostile chemistry is acting on him. The medicine blocks the adrenaline receptors, and the body riots and begins to grow more and more new adrenaline receptors so as not to miss a single stray adrenaline molecule.
That is, while taking beta-blockers, there is a continuous competition between the growth of more and more adrenaline receptors and the blocking of these receptors by the drug.
Usually already half of these receptors will wither like delicate flowers in 24–36 hours. If a person ate a short-acting anaprilin, which after a few hours will no longer be in organism, then after these few hours in the body there will still be a whole plantation of unfaded receptors for adrenaline. There is no medicine anymore, but for a whole day or longer, a bunch of receptors will grab the adrenaline floating by and show all the bad properties of this adrenaline.
But on the other hand, if a person took the gorgeous Concor, then this Concor will be withdrawn from him for three days. And by the time of complete withdrawal of Concor, all receptors have already faded. Therefore, a vivid withdrawal syndrome may not work out. Now you understand why you have to pay for Concor?
In general, withdrawal from clonidine and beta-blockers is different.
After the abolition of clonidine, blood pressure usually rises sharply, and much higher than the initial level. That is, overkill.
After the abolition of beta-blockers, not only the pressure rises, but also the work of the heart increases. From this there can be angina pectoris, myocardial infarction and you can die. It's funny that a heart attack sometimes happens to those who did not even complain of heart before stopping the beta-blocker.
To prevent this from happening, both clonidine and beta-blockers are gradually canceled. About a week. Or even 10 days. Remember when we discussed how to safely discontinue medication? The dose is also reduced by 2 times, but here every 2-3 days. But that doesn't always help. Sometimes the medicine has to be returned.
Familiar situation?