A physician with 23 years of experience parses an article in the authoritative journal Nature - only proven information
There is growing evidence that the Sputnik V vaccine is safe and effective.
Most important from an article published in a reputable journal Nature:
- Russian vaccine against COVID-19 "Sputnik V", developed by the Gamaleya Institute, used in nearly 70 countries.
- Data from Russia and many other countries indicate that the vaccine is safe and effective. But there were some questions about side effects that are quite rare.
- Actually, because of this, she has not yet received World Health Organization endorsements. WHO has requested additional data from the Gamaleya Institute, and is currently conducting inspections of both Russian vaccine production facilities and clinical trials.
- Sputnik V is an adenovirus vaccine, as are Oxford-AstraZeneca and Johnson & Johnson. The difference is that Sputnik V uses 2 different adenoviruses - rAd26 (for the first injection) and rAd5 (for the second). This is for improving the effectiveness of the vaccine.
- The vaccine was approved for use The Russian Ministry of Health on August 11, 2020, more than a month before the publication of the results of the Phase I and II trials and even before the Phase III trials began. This drew criticism.
- However, some of the fears were allayed in February 2021, after publications intermediate results of phase III tests. The vaccine was on 91.6% effective in protecting against COVID-19 and 100% effective in preventing severe infection.
- Several countries, including South Korea, Argentina and India, have already produce "Sputnik V". In many countries, such as Hungary and Iran, Sputnik V has become a key element of their vaccination campaign.
- In April 2021, the Gamaleya Institute released Press release, Whereby vaccine efficiency - 97.6% according to data on 3.8 million Russians vaccinated with two doses.
- Data published By the Ministry of Health of the United Arab Emirates, 81,000 people who received two doses of the vaccine show 97.8% effectiveness in protecting against COVID-19 and 100% effective in preventing severe disease.
- Even one dose of the vaccine provides 73.6% efficacy to prevent the moderate to severe course of COVID-19, which led to the approval of the single-component vaccine Sputnik Light (vector rAd26) in May.
- There is a study by the Ministry of Health Argentina, held in Buenos Aires with 40,387 vaccinated and 146,194 unvaccinated people aged 60-79, which says that one dose of the Sputnik Light vaccine reduces the incidence of the disease by 78.6%, the number of hospitalizations by 87.6%, and the number of deaths by 84,7 %.
- The question with side effects. They are similar to the side effects from Oxford-AstraZeneca and Johnson & Johnson, but there are noticeably fewer cases of thrombosis.
- IN scientific article preprint from the private Hospital Italiano de Buenos Aires in Buenos Aires, which analyzes the Sputnik vaccination experience of 683 health workers, no no mention of a bleeding disorder or adverse eventof particular interest.
- There is data from Brazil on the results of the introduction of 2.8 million doses of Sputnik V. And there no vaccine-related deaths, there are mild side effects.
- IN preprint about the experience of San Marino no serious side effects identified in 2,558 adults who received one dose of Sputnik V vaccine; and 1,288 people who received two doses.
- There is theory on the link between blood clotting disorders and vector vaccines, but it is unclear how much this affects Sputnik V.
- The vaccine is now widely used all over the world, which means that all side effects will be identified.
- Argentina did not report not a single case of thrombosis in vaccinated people despite receiving more than four million doses of the vaccine. Serbia, which also uses Sputnik V extensively, has also not yet reported cases of thrombosis with other adenovirus vaccines.
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