I'll tell you about gels with non-steroidal anti-inflammatory drugs, and you yourself decide who is lying here.
Nimesulide and Meloxicam are referred to as selective non-steroidal anti-inflammatory drugs. That is, they should irritate the stomach less and provoke less bleeding. This would be beneficial for people with chronic joint pain. For years they have been swallowing different chemistry, and even a slight indulgence in their long-suffering stomachs is very welcome.
Do you think Nimesulide and Meloxicam are very powerful drugs? That's right, they are not as powerful as the old and proven simple non-selective Diclofenac, Ketoprofen, or Ibuprofen.
It is understandable, the selectivity of Nimesulide and Meloxicam is due to the fact that some of their activity was taken away. They are slightly cast, which is why they are so soft and tender. Like eunuchs.
Diclofenac with Ketoprofen in this sense are simple and brutal. But the rudeness of Diclofenac with Ketoprofen does not allow taking them for too long without harm to the stomach.
For some situations, there was a clever way out. Anti-inflammatory drugs began to be produced in gels and ointments. This helped patients with osteoarthritis.
In this form, non-selective drugs had enough strength to break through to those joints that lie close to the skin. For example, to the knee joints and the joints of the hands.
Non-selective drugs are powerful enough to penetrate the skin into the joint and have an anti-inflammatory effect there. It is difficult for them, but they often cope.
If you are lucky, this will be enough, and patients will not have to swallow pills.
It is also important that topical drugs are very reluctant to be absorbed into the bloodstream, so there is no great harm to the stomach. It turns out that the wolves are fed and the sheep are safe. The beauty!
Now about what I personally do not understand. I know for sure that a gel with Nimesulide or Meloxicam is sold in pharmacies. So what's the point?
The beauty of Nimesulide and Meloxicam is to take them internally. They are weak, but win over long distances, when you have to swallow pills for years. So why try to force these castrates to storm the skin and forcefully penetrate the joints? They're goner.
This is the question of lies.
Now I have a proposal for you. Someone asked about Fastum Gel. Let’s try to figure out how effective this gel will be when rubbed into the knee joints. Will you try? Look at its composition and think.
