When it comes to acne, the matters are primarily those of our hormones, then - power. And only at the end of diluted debate about their exterior treatment, which, frankly, underestimated by many.
And if in the end it turns so that the hormones we all normally, no glitches in the endocrine system, no power in our correct, corrected, but her face remained shine with rashes that began to appear intensified?
Then will dig in the direction of increased work of 5-alpha-reductase. That we have such an enzyme that converts testosterone to dihydrotestosterone, it has a direct influence on the development of the sebaceous hair follicle protection. The enzyme 5-alpha-reductase is working not only on the scalp, but also on the face.
Many who have experienced acne, take drugs prescribed by the doctor in the form of creams or pills. It seems to be good, rashes disappeared, but a month later, even while continuing course of treatment with the drug rash of new continued. Someone has even intensified. And because everything is done according to the instructions and use products can be up to 12 weeks, but still went to the rash.
And here is where the fun begins. Not only for dermatologists, but also for those who suffer from acne. I still do not understand why so little information about the phenomenon of resistance of microorganisms. Simply put, it is when some bacteria that cause acne, begin to unite in a biofilm.
It is so powerful bacterial film that is not so easy to destroy it: the bacteria are combined with each other, themselves produce the polymer matrix and is formed on the skin surface of the living. Biological film consists of:
1) the bacterial environment that is just struggling with antibiotics prescribed by dermatologists, it just does not give the active components of the drug to reach their destination. The composition of the extracellular medium also includes polymers which, in turn, consist of water, cell wall components and oxidation products;
2) the bacteria themselves, that "pleasing" human acne and show their power to the powerful drugs that are supposed to kill them.
Protection of antibiotics against acne - a small part of what the worth of such biofilms. They release substances that our body is alien (called antigens), it is cause inflammation: a biofilm develops antigens and the body is protected from them, producing antibodies. And the field of battle antigens with antibodies is our skin face and head. However, our body's protective arms weaker than biofilms: an antibody as a result of losing, the surrounding tissues are damaged and serve as a place for new colonies of bacteria.
Sooner upset, this is not a sad end to our beauty-action movie. The next article will discuss how people manage to defeat this bad biofilm. If you are waiting for the continuation of - place "thumbs up" to the article, not to miss the second part.
