First genetics faced with a situation where the baby was found blood group, which could not be inherited from parents, in 1952. The man-father had blood group I, a woman-mother - II, and the child was born to them with blood group III. according to genetic researchthis combination is not possible. The doctor, who had been watching the couple suggested that the child's father was not the first group of blood, and its imitation, which has arisen due to some genetic changes. That it is changed gene structure, and therefore - the signs of blood.
This also applies to the proteins responsible for the formation of blood groups. A total of 2 - it agglutinogens A and B, located on the membrane of red blood cells. Inherit from their parents, these antigens to create a combination that defines one of the four blood groups.
The Bombay-based phenomenon - recessive epistasis. In simple terms, under the influence of mutations blood shows signs of I (0), since it has no agglutinogens, but really is not.
How can you determine what you Bombay phenomenon? Unlike the first group of blood when there is no agglutinogens A and B on the red blood cells, but it has agglutinins A and B in serum in patients with Bombay phenomenon determined agglutinins defined group of inherited blood. Although the red blood cells of the child and will not agglutinogen B (reminiscent of I (0) blood group), but the serum will circulate only agglutinin A. This will differentiate blood from Bombay phenomenon from the usual, because normally in individuals with I group have both agglutinin - A and B.
If the need arose blood transfusion in patients with Bombay phenomenon can be poured only exactly the same blood. Find it for obvious reasons it is impossible, so people with this phenomenon, as a rule, retain their own material on the blood transfusion stations, in case of need it use.
If you are the owner of a rare blood type, at marriage necessarily tell your spouse, and when you want to acquire offspring, consult a genetics. In most cases, people with Bombay phenomenon of children born with normal blood group, but does not correspond to the recognized rules of the science of inheritance.
Also you will be interested to know, that actually affects the human lifespan.
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