It turns out that people who are prescribed thyroxine with omeprazole adhere to some cunning, and even I would say pretentious schedule of taking these drugs.
The problem is that both omeprazole and thyroxine should be taken about 30-60 minutes before breakfast. It is also known that omeprazole reduces the effectiveness of thyroxine. This throws people off balance, and they begin to calculate the reception time with a stopwatch in their hands. Someone sets an alarm at night to drink thyroxine at 4 o'clock in the morning.
I confirm. Omeprazole interferes with thyroxine absorption. This means that if you have to combine the reception of omeprazole with thyroxine, then the endocrinologist will add a headache in the form of additional tests and adjustments.
Only you, brothers, misunderstand the essence of this interaction. Omeprazole does not attack thyroxine and does not interfere with its absorption into your blood. These two drugs won't fight in your stomach like gladiators in the arena. No. It's all about the acid.
If there is little acid in the stomach, then thyroxine is absorbed worse. Omeprazole reduces the amount of acid in the stomach. The amount of acid decreases within an hour after taking omeprazole and continues for 72 hours. If you stop taking omeprazole, the amount of acid will return to normal levels in 3-5 days.
Since the effect of omeprazole lasts longer than a day, there is no point in spreading its intake with thyroxine during this day. Got it?
The thyroxine tablet will work for you for a week, and the omeprazole tablet will work for you for several days. The absorption of today's thyroxine is influenced by the day before yesterday's omeprazole. Therefore, there is no point in taking them away as fighting drunks. Take them together 30-60 minutes before breakfast.
There are no hard and fast rules for taking thyroxine with omeprazole, so different doctors will suggest different regimens for you.
Read my other articles about omeprazole: