How Nexium differs from Omez. Nothing. Another trendy switch to chiral molecules

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It was suggested that Nexium had fewer side effects than Omez. I cannot agree with this.

The fact is that Nexium is about the same omeprazole as in Omez. Someone in the background is outraged that in Nexium it is not omeprazole, but esomeprazole.

Esomeprazole is actually the levorotatory isomer of omeprazole. That is, omeprazole is a mixture of two molecules that have the same formula, but are oriented differently in space. Like right and left hand.

The drug manufacturers wanted to improve omeprazole and split it into a more active and less active isomer. The active isomer of omeprazole was called esomeprazole, packaged in boxes with the name Nexium and stuck on the boxes with a price tag 10 times higher.

This approach is called switching to chiral molecules. Chirality is a chemical term where two molecules are nearly the same but cannot fit together in space.

The best example of chirality is as if you wanted to shake someone's left hand with your right hand. Does not work.

In short, the fashion in medicine has gone to make the so-called "switching to chiral molecules". It's kind of good. In fact, it is at least expensive, and in the case of omeprazole, it is economically completely unprofitable. Ordinary omeprazole from a mixture of two isomers has already been tested far and wide. He saved many lives. The benefits of esomeprazole are in dose only. It's not worth it.

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The most interesting thing is that the number of side effects from Nexium is likely to be higher than from Omez. Because Nexium is about the same thing, only more active.

Well, that is, if your stomach hurts from milk, then the concentrated cream will hurt your stomach even more. Concentrated Nexium can also have more side effects. Got it?

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