Why the legs swell less from the Equator than from the usual amlodipine

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In peaceful life, the equator is called the belt on the belly of our planet. But then they ask about a medicine called Equator. Everyone's favorite amlodipine is hidden in it, from which, according to some readers, the legs swell less.

I don't think Gideon Richter did some unusual amlodipine. Rather, the matter is in the second component of the "Equator".

On the merits of the above appeal, I explain that the so-called "Russian amlodipine" was not noticed, was not involved and did not take place. In other words, this drug can indeed cause swelling in the legs, but no more than all other foreign amlodipines.

The cause of swelling in the legs of amlodipine users is hidden in the very essence of the drug. Amlodipine dilate small arteries and thereby lowers our blood pressure. The problem is, he does it too well.

Screaming hordes of erythrocytes rush through the dilated arteries towards the capillaries, which carry out all the doors in their path and even spoil the walls. From the walls of the capillaries begins to flow, and the liquid part of the blood seeps into the intercellular space. This is how swelling occurs. About the same story we discussed in the topic

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about swelling of hands in the heat.

So, by an interesting coincidence, in addition to amlodipine, lisinopril was added to the Equator tablet, which is able to expand the small veins that depart from those very leaky capillaries.

It turns out that amlodipine launches a crowd of aggressive erythrocytes into the capillaries, and lisinopril opens the exit doors for them so that they can calmly pass through and not break anything. A very clever solution. And you will not find fault with it, because this is a completely approved combination of drugs.

It seems to me that this is precisely the case. Well, because I don't believe in drugs without side effects. They all have side effects.

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