Ancha Baranova explained the effect of famotidine on viruses. To begin with, two types of drugs are used for heartburn: the type of omeprazole, which reduce acidity, and the type of famotidine, which reduces the activity of gastric enzymes like pepsin. And so people can get indigestion from famotidine. Well, because enzymes won't digest food. But at the same time, an attack of heartburn is stopped. What pleases patients with heartburn. But, according to Anchi, famotidine will also suppress the activity of enzymes that help the virus to shed excess proteins from itself. And it lowers the viral load.
This is all wrong. Gag. I explain. Both omeprazole and famotidine reduce gastric acidity. Enzymes have nothing to do with it. Heartburn is caused by the action of acid on the lining of the esophagus. Therefore, heartburn from drugs that block the secretion of acid in the stomach decreases.
Omeprazole and famotidine do act differently in this regard.
Omeprazole blocks the proton pumps, which pump positively charged hydrogen ions into the gastric juice. These hydrogen ions are pure acid.
Famotidine is classified as an antihistamine. It blocks H2 receptors for histamine.
Histamine is a biologically active substance that normally binds to H2 receptors and causes the stomach glands to secrete more acid. If you block the receptors, then the stomach will not know anything, will sleep peacefully and will not secrete acid. The acidity of the gastric contents will decrease. If the contents of the stomach enter the esophagus, then it will no longer burn it so cruelly, and people with heartburn will be happy.
Does famotidine cause indigestion? No. It has no effect on enzymes in the stomach. Well, that is, when it blocks the receptors, then less gastric juice will be secreted into the stomach. But the enzymes were infernal, so they will remain infernal. Famotidine does not affect the enzymes themselves. So here by the checkout.
And here are the viruses
Someone noticed a year ago that covid patients die less often on famotidine. Famotidine basically protects seriously ill people from stressful stomach ulcers and all that. So they know him by sight.
So there was an opinion that famotidine itself somehow directly acts on enzymes in cells that help the virus to change clothes. But this was not confirmed later. Do you hear? NOT confirmed. You can forget about enzymes.
Then there was the idea that famotidine in covid patients actually acts on its own H2-receptors for histamine. That is, its standard action. Like there, in seriously ill people, histamine can also rage, and from this they often die.
Then studies began to appear that did not find anything so useful in famotidine. Rumor has it that some scientists just wishful thinking. That is, with famotidine in relation to viruses, nothing is clear at all. So you can forget about this case.
Understand, brothers, many people (both doctors and scientists) grabbed at any straw in order to oppose at least something to covid. Thousands of encouraging studies were clocked, but then most of all these interesting results were not confirmed. So forget about famotidine.
