I'll tell you what is good and bad about it.
American Pfizer is one of the world's largest pharmaceutical giants. He made a messenger RNA anti-toxic vaccine. This is one of the latest fashion trends.
The meaning of messenger RNA is that if it is inside our cell, then our cell begins to stamp the protein encoded in this RNA.
Under normal conditions, our genes are encoded in the form of DNA, packed in chromosomes, and all this economy is hidden in the nucleus of our cells.
If our body wants to shake some of its genes, then the body makes messenger RNA. It is like a mold or an imprint from some piece of DNA.
And so the informational RNA in the form of such an imprint falls out of the nucleus and goes to a special factory for the production of protein inside the cell. Based on information from this RNA, tiny devices inside our cells churn out proteins.
It was the natural way. Top - down from the cell nucleus. Now about the messenger RNA vaccine. It delivers RNA to the cell through... another place.
The Pfizer vaccine is an RNA that carries information about a viral protein. This RNA does not come out of the nucleus of our cell. Not. It floats in the blood after the injection and is gradually swallowed by our cells.
The tiny protein factories in our cells think it's our native RNA that has come out of our cell's nucleus and begin churning out the protein encoded in the RNA. This will be the protein of the virus.
Immunity will quickly detect such counterfeit production and start producing antibodies. This is how we get protection against viruses.
What's good about the Pfizer vaccine
It has to get inside our cells, but it doesn't have to get into the nucleus of our cells. That is, instead of two barriers, she only needs to overcome one barrier. Therefore, it works faster than vector vaccines.
It does not enter the nucleus of our cells, therefore it cannot cause any mutations there. Some of the experts are hinting that vector vaccines can stick their information somewhere in our DNA, and a failure will begin, and almost oncology will grow. They scare.
RNA itself is very infuriating to our immunity. If it detects RNA in the blood, it is quickly activated. Therefore, such a vaccine does not require any aluminum adjuvants. She herself is like a brutal adjuvant.
What's wrong with the Pfizer vaccine
It strongly stimulates the immune system and, for the same reason, can provoke the development of autoimmune diseases.
All covid RNA vaccines from different manufacturers indicate the possibility of facial nerve palsy. This is rare, but it does happen. Therefore, this case is being watched.
Our blood vessels hate free RNA floating in them. This is unnatural for our body. The RNA must sit inside the cells and not float in the blood. For some reason, this causes damage to the cells of the inner lining of blood vessels, and thrombosis is obtained.
The Pfizer vaccine is a smart way to stimulate the production of antibodies, but it does not really know how to stimulate cellular immunity. This is because it does not go into the core.
Our immunity does not like it very much when someone climbs into the nuclei of our cells. He immediately lowers all the dogs to this business. Including cellular immunity. So the advantage of RNA vaccines that stay out of the nucleus may become a disadvantage.
No one knows exactly how important cellular immunity is in covid. Our vector vaccine Sputnik spurs it on. But the American one does not know how.
In any case, the messenger RNA-based Pfizer vaccine should be safer than vector vaccines. This is in theory. In practice, we'll check it out. There were actually two Pfizer vaccines. But then one had to be abandoned due to side effects.
You can read about other types of vaccines:
About different vaccines and first about the Sputnik, with which we became related yesterday
About Chumakovskaya and Vektorovskaya vaccines, and about my third day with Sputnik
