How does Botox and why some celebrities after it "distorted" faces

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"Liza! Illiterate magpies are not able to open the same Wikipedia and see if it's true. They just sensational stuff in magazines and on TV"- these words are familiar to a dermatologist, I remember when our conversation went about injections in the future, when it knock 30 and whether such serious injection procedure, because terrible it will help out anyway (no, not scary stabbing and age). Botox opponents, as it turns out, plenty of (well done media, great job!).

And it is not a beautician, it makes no sense to promote the beauty injections, she has another area of ​​work. But I agree that many do not have anything of interest to study, dig into primary sources, to weigh all the "pros" and "cons."

I have long developed an immunity to all sorts of media. On Web sites, it is important to high attendance, and has long been in practice has already been tested that are gaining momentum only shocking and sensational material. Why write as good looking pop star and occasionally indulges in Botox, when only one material with a failed procedure? Such material will bring media site every day a huge number of visits for even a few months and a few years!

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Also, I am not convinced of the research scientist and founder of unknown garage startup, which was attended by 5-10 people (mom, dad, me and my friends). Rather, it is to remind once again delve into the topics and learn new. Troika my favorite sites, if I want to learn something in cosmetology - WHO, the NCBI and Wikipedia, where I can spy on the sources from which all the information is gathered. Next to me is not difficult to ask doctors (acquaintances in Direkte instagrama, e-mail), compare all the facts (or rather, her husband will help me a lot is often difficult to digest) And draw some conclusions.

My personal opinion about Botox as follows: when will come the same day, when "ALL, IT'S TIME" - do.

This can be in 40 years, maybe 50. Or later, I do not know. So far so good (pah-pah-pah). Yes, I do not want to see myself in the mirror with the old Bryl, wrinkles, etc. etc. And if I am pleased to see themselves young - then I turn to cosmetologists. The selection of each. I do not impose anything on anyone. It's not my - test pharmaceutical agent rejuvenation for 15-50 rubles, the effectiveness of which, firstly, nobody in fact has not been verified, and secondly - in such articles photos "before" and "after" are borrowed just at beauticians.

If Google does not horror stories with Botox, and the actual results of work, you can stumble upon women who are much more beautiful. And with the fact you can not argue, as it were, the opponents of this injection did not want to do ;-)
If Google does not horror stories with Botox, and the actual results of work, you can stumble upon women who are much more beautiful. And with the fact you can not argue, as it were, the opponents of this injection did not want to do ;-)

And all the horror stories about Botox (as the doctors have told me here, and for me as it seems to be true) Is mainly fabricated cosmetics manufacturers because often Botox is cheaper external creams premium to super-active compounds, based on the quality of the result. Botox for them not just a strong competitor, he would have easily destroyed the business of manufacturers of anti-aging creams. But the information - a powerful weapon, and the time they took advantage of manufacturers of outdoor and allegedly "anti-aging" cosmetics. A peredutye Mukla in Instagrame - here fillers to blame, not Botox.

Something I have suffered :-) Okay, go to the mechanism of work of Botox.

A small disclaimer in e few adequate commentators with elevated insulin, which can do nothing constructive dialogue, not the normal communication (from where you have so much anger - is unclear, and no wonder, as other people): It painted the mechanism of how the Botox. If interested, you can dig themselves in the materials (not on questionable Women's Forum, a little string up to the original sources) - to be told the same thing, that here, but less accessible language. So... God we love trio, huh? So once again I will write twice to make up this caste commentators came: the article is painted only mechanism of Botox are no advertising or public relations, or Antipiar. One more time, let's - painted the mechanism of Botox. Whoever does not understand, unfortunately, this is not my fault :-)

The mechanism of operation of botulinum toxin (as simple words)

Many people have only heard or read about the fact that it blocks muscle. But this is not true, we are now with you kopnom deeper.

Between the nerve and the muscle is, simply, the communication channel. This channel transmits a signal acetylcholine. That's just Botox does not reach the end of acetylcholine from the nerve to the muscle receptor. Because of this, the muscle fibers are relaxed.

Now look interesting shemku below.

Our courier signal from the nerve to the muscle, acetylcholine, in the illustration Set green dots. At rest, it is in the synaptic bladder (gray circles). When we wince and wonder at all at any mimics acetylcholine "going to work" - he has to get out of their synaptic bladder muscles and deliver the signal from the nerve endings.

On the way to the muscles, he falls into the synaptic cleft (the diagram - it is an empty space between the nerve and the muscle at the top of the bottom). He needs to "get into the embrace of" muscle receptors to transmit a signal to decrease. Receptors on the scheme - such blue claws.

That's just got to acetylcholine in the synaptic cleft, we must still somehow get him out of the "house" (the synaptic bladder) and the nerve to cross the border. This signal helps our courier special protein - SNARE. He opens the door of acetylcholine in the bladder and on the border of the membrane of the nerve, so he quietly entered into the synaptic cleft for a meeting to the receptor.

And that's just one of the botulinum toxin interferes with protein in the SNARE complex compound to give an opportunity to open the doors to our courier signal. Acetylcholine because the toxin can not connect to SNARE and go beyond the nerve.

That's how the toxin works, it blocks the protein work, not muscle. it does not interact with them.

Organism even a tiny dose administered Botox processes for 15-20 minutes. It only recycles! The effect itself immobilize muscles acting on average 4-5 months. Only there is no longer reason to Botox, but in time restore the previous work of the nerve endings. A very important point, because I have Botox disappears from your body in half an hour, all rest of the time - it's the nerves come to life, someone they oklemalas 3 months, and someone - 5 months.

Here, he dispelled another myth about the fact that after the injection, the person goes to a toxin in the face a couple of months. That's bullshit.

Now, about the fear that the nerve endings after Botox atrophy. It is also a myth, because Botox disables the usual work of acetylcholine. To return to the previous working channel, nerve endings start the regeneration process to make new processes that help our courier "return to work". Once these processes have helped him - they die off as superfluous, and everything becomes as before. Until the next "hooliganism" Botox.

I'll describe all that is written in the medical literature or Wikipedia. Glossy magazines did the shoddy and sloppy - they write about blocking muscle, and this we already skittish people perceive danger for another :-)

Skewed purportedly from Botox celebrity

One obvious reason - the "left" products, under which can get as a simple patient and celebrities. But the main reason for skewed persons - bust of fillers with gialuronka. Just imagine: filler fills the volume on your face and Botox reduces facial expressions, so it turns the face mask (smooth skin without wrinkles, providing padding gialuronka volumes, and then there was the inability to stretch the muscles in addition person). And by the way, a lot of conflicts arise between the beautician and amateur fillers, Botox.

The specialist knows exactly how many times a year should do injections, and the man is so accustomed to his smooth face that he does not want to ever it superfluous to see wrinkles, hence the growing appetite in eternal rejuvenation, which will result in the fact that here is a man with the face of a mannequin or skewed.

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