Blockers, proton pump (PPI) are called group of drugs which inhibit acid secretion in the stomach.
Acid becomes acid due to hydrogen ions. The core consists of a hydrogen atom from a single proton, however, positively charged hydrogen ion called proton.
In the stomach secreted protons proton pump. Ie proton pump - it pumps that produce acid. Proton pump blockers inhibit this secretion.
The less acid, the faster restores damaged stomach, esophagus, duodenum. That is, these drugs do not stick with a hole in the stomach. They just give your stomach a break. When no acid would read mucosa, there occur recovery processes all heal and will not match.
To blockers, proton pump worked, they should safely be absorbed into the bloodstream and find yourself active proton pumps.
If blockers, proton pump fall into the stomach with food, the movement of the stomach (motility) and highlight the acid will destroy the drug.
The amount of proton pumps will be maximal after prolonged fasting. They grow in the stomach, like mushrooms in the morning after a night of rain. Therefore, it is most advantageous to take proton pump blockers in the morning on an empty stomach. Then they are absorbed into the bloodstream intact and be able to find for themselves the maximum amount of the proton pump.
Blockers, proton pump can only operate on the active pump. Before meals remain active only 10% These proton pumps. We have to somehow get the pump to work.
Pumps run at meal time, so after 30 - 60 minutes after taking proton pump blockers necessarily need to eat. This hour is needed in order to suck the medicine into the bloodstream, sailed with the blood flow to the stomach and clung to the proton pump.
Food activates pump blockers inhibit these active pump and acid in the stomach becomes smaller. Blocked pump will not release acid a day. The maximum effect of this treatment is developed 3 - 4 days.
In most cases, single dose of proton pump blockers. It is best to take these drugs on an empty stomach in the morning. After 30 to 60 minutes after taking be sure to eat breakfast. Such conditions provide the desired effect.
If you take a proton pump blockers in the afternoon, then the effect will be weaker.
If you take a proton pump blockers in the morning on an empty stomach, but then a few hours is not, the medication simply will withdraw from the body and will not work. Therefore, observe the rules.
Some blockers, proton pump sold in pharmacies without a prescription. These drugs are not as harmless as many people think. Chronic administration may provoke the development of tumors of the stomach and damage the kidneys. Therefore, if you have to take them often, be sure to consult with your doctor.
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