It is well known that patients with diabetes, the risk of developing certain types of cancer (breast, ovarian and others) several times higher, and scientists can not possibly explain this correlation. But it seems that now this secret has been revealed, reports etozdorovo.top
Read to the end to get the most useful information.
It has been suggested that the likelihood of developing cancer increases due to hormone disorders. Thus, patients with type II diabetes, insulin does not provide efficient transportation of glucose into the cells. Thus, the pancreas produces more and more insulin, and develop hyperinsulinemia. In addition to monitoring blood glucose, insulin can also stimulate cell growth, which can lead to tumor growth.
In addition, the majority of patients with type II diabetes are overweight. In this regard, the excess adipose tissue produce higher levels of hormones adipose tissue adipokines than those with a healthy weight. Adipokines cause chronic inflammation, which is also associated with carcinogenesis.
These theories seemed logical, but only recently American scientists have found that due to the increase in blood sugar levels increases the risk of DNA damage - the likelihood of damage to genetic material is much lower than in people with normal glucose levels in blood. It is known that DNA damage increases the risk of developing cancer.
The authors of the theory confirmed this version, finding in mice with diabetes, a certain type of damage in the form of compounds of "extra" DNA molecules, which are known as adducts. In the tissues they found DNA adducts of a certain type, CEdG, encountered in the "diabetic" tissue more often than normal. They also found that elevated levels of glucose enhances formation process such unnecessary molecules in cells and interferes with the normal DNA repair process (repair).
In addition, the study authors suggested several medical methods for correction of abnormal formation CEdG, although many of their ideas still have to translate pharmacology. So far, scientists remind us that there is a simple and affordable way to reduce cancer risk in diabetics - adequate control of blood glucose.
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