Rumor has it that someone does this. Do you know why they do this?
They want to remove the reservoir of the virus from the nose, prevent it from attacking others and mutating.
In general, the idea of a vaccine for instillation in the nose is not new. So they were vaccinated with a live influenza vaccine. As a result, it would be possible to interrupt the circulation of the influenza virus, protect others, and prevent the virus from mutating.
The satellite smartly develops immunity inside the lungs. This prevents people from dying of pneumonia. But vaccines like Sputnik, which are injected into a muscle, fail to build powerful immunity in the nose. That is, people vaccinated by the Satellite can become infected with the virus and can transmit it to others. The likelihood of this is low, but it is.
To protect against infection with covid, a person needs to deliver the vaccine directly to the nose. In theory, it would be necessary to inject there a live weakened vaccine. But now, when the virus is already mutating in South Africa or elsewhere, it would be somehow not entirely logical to design a new live virus, even if weakened. What if he runs away and runs wild? We ourselves will make ourselves another mutant.
In short, there was an idea to pour Sputnik into the nose.
Personally, it seemed to me that this was some kind of wild amateur activity, but it turned out that the Americans had already "announced the planning" of the first phase of trials of a vector anti-toxic vaccine for infusion into the nose.
The vaccine is called AdCOVID. The vaccine manufacturer's website is very streamlined. And the fact that it is vector can only be understood from the stories of journalists or by indirect indications. Maybe I didn't read something there, but the manufacturer compared his vaccine with "other vector" ones. It turns out that it is also vector.
But the effect of this vector vaccine is somehow very streamlined. It acts on many links of immunity, and the titer of antibodies is good there. The truth of which antibodies and against what is somehow incomprehensibly stated.
Personally, I am plagued by vague doubts that this immunity will not be very suitable specifically for covid. But if the vaccine is a vector vaccine, then it will not be able to escape and run wild. This is already good.
It turns out that the idea of sputtering Sputnik in the nose is not so wild. This turned out to be news to me.
What's wild? Well, twenty years ago, they tested an adenoviral vector-based nasal vaccine against HIV on mice. There, the researchers doubted whether the vector would fly from the nose directly into the brain and spoil something. I don't know how it ended there.
Have you heard about this?
