Someone really scared people, because I was asked three times this week about the vaccine and antibody-dependent intensification of the infection.
I explain. Antibody-dependent intensification of infection is when antibodies against a virus appear in the blood, but this only makes it worse. That is, they injected a person with a vaccine, and he died from it.
The point of such a horror story is in the production of the wrong antibodies.
The correct antibodies are called neutralizing antibodies. That is, the virus enters the bloodstream, neutralizing antibodies stick around the thorns of the virus, and the virus cannot do anything to us. It is then swept out of the body like garbage, and this is where the whole infection ends.
But antibodies are also wrong. They cannot block the spikes of the virus, but simply flag the virus. The virus does its nefarious job, but it is also noticed by the immune system.
It would be if the virus, like a mad bull, smashed everything around, and they would also hang a bell to attract attention. People come running to the ringing, and the bull not only carries everything, but also butts the crowd of onlookers. That is, there is more harm from the bell.
The wrong antibodies act as such a bell. They attract immune cells, they swallow the virus, but he lives quietly in them, and even multiplies. Then it turns out that the virus on these immune cells traveled like a bus to the place it needed.
Or another option. Wrong antibodies stick together some of the viruses in a heap, attract immunity there, and an increase in inflammation is obtained. This only makes the patient worse.
Now about covid
The first variant of antibody-dependent enhancement of infection with covid does not work. And this is good. That is, the virus cannot ride on our immune cells like on a bus.
But the second option can unfold in full force. This is exactly how, by increasing inflammation in the lungs, covid kills people.
Now about vaccines
Any vaccine foolishly can provoke an antibody-dependent increase in infection. But vaccines are always tested for a start on a whole army of different-sized rodents, so suspicious options are screened out.
In addition, vaccines against covid are specifically designed to produce large amounts of neutralizing antibodies. So they will immediately stick to the virus, and there will be very few defective antibodies.
The weak link here is inactivated vaccines like Chumakov's or a couple of Chinese ones. These vaccines stimulate the production of various antibodies, and not necessarily neutralizing ones.
In any case, the existing anti-toxic inactivated vaccines have been tested, and they seem to work correctly. So antibody-dependent intensification of infection with modern vaccines is not threatened.
Unvaccinated people are another matter. There is a chance that cross-reacting antibodies from viruses that cause the common cold could provoke something like this. So you better get vaccinated and build yourself a good supply of neutralizing antibodies.
