Why are antipyretics dangerous for liver disease

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Sooner or later, everyone has to lower their body temperature. No one is immune from colds and other infections. Among these "all" there will certainly be people with liver diseases. So what to do with them?

The story immediately comes to mind about poisoning with paracetamol, which in a large dose completely destroys the liver. Scary.

Non-steroidal anti-inflammatory drugs like ibuprofen or aspirin can also harm, and in several different ways.

We've discussed bleeding from aspirin more than once. From it there are gastric bleeding and hemorrhage in the brain.

A sick liver produces few proteins. Including clotting factors that stop the blood. Therefore, patients with cirrhosis may experience unpredictable bleeding. Aspirin is somehow out of topic here.

And in patients with cirrhosis, the veins in the esophagus dilate. Therefore, swallowing caustic tablets like aspirin is also dangerous for them. If such a vein bursts, then the bleeding is difficult to stop.

Ibuprofen and similar medications do not work as badly as aspirin, but they can cause bleeding. This is because they are related to the non-steroidal anti-inflammatory family.

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Still non-steroidal ones are dangerous by impaired renal function. Remember, we discussed with you dehydrated patients who stop filtration from ibuprofen in the kidneys?

So, against the background of liver diseases, all this happens much stronger and harder. The liver itself is able to disrupt the work of the kidneys so that they stall and stop.

You can also remember analgin. But he was so lowered in the 60s that they are still very afraid. Analgin sometimes damages the bone marrow.

For the liver, he is also not completely indifferent, but we will not learn anything about this for a long time, because analgin is stupidly not included in scientific research. There is simply no information about him.

It is clear that people with liver disease need to take only what the attending physician prescribes.

But now I have to choose something from the listed drugs. So here's a backfill question for you:

Which one should we choose from aspirin, paracetamol, ibuprofen or analgin for serious liver disease?

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