American scientists have known through the publication of Proceedings of the National Academy of Sciences to share with the international community the results of laboratory experiments on mice with a completely new anti-tumor vaccine. When administered to rodents suffering from melanoma, the drug together with a known drug gave 100% cure of. The authors of the study are convinced that developed the vaccine in the original combinations of various means can be used to combat effectively with other types of aggressive malignant tumors.
Dale Boger (Dale Boger) - Professor AI Scripps (USA) explains to the uninitiated: "A new drug for the vaccination, we used in conjunction with diprovotsimom - known drug that stimulates the immune response of any body. That is why the fight against cancer cells was very effective, because the EC correctly recognized a tumor cell, and then just eliminate them. The same strategy has been to date, and for the relief of Cancer recurrence. "
In a sensational experiment involved 24 laboratory mice, each of which was observed at the beginning of the experience of an aggressive form of melanoma. All rodents were obtained anti-PD-L1-therapy involved drugs based on antibodies.
For the objectivity of research testers animals were divided into three groups of equal numbers - 8 mice each. The first cohort received the vaccine in combination with diprovotsimom. The second - the vaccine in combination with some other drugs. A third - pure vaccine without impurities. Thus the basic drug is injected directly into the tumor rodents.
During laboratory experiments, all mice received 2 injection with an interval in a calendar week. At the expiration of 54 days from the start of the experiment, scientists have made a mark on the:
- a 100% survival of the animals of the first group;
- the death of 75% of experimental animals in the second group;
- zero and survival of rodents from the group № 3.
As soon as the Americans planned clinical trials of a new vaccine. As well as experience on the use of the drug developed in combination with a variety of drugs.
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