We will not remember any tranquilizers and antidepressants here. Of all of them know that they may cause drowsiness. Sleep may be disturbed only if such medicines first for a while to accept, and then cancel. It's a boring story. Let's talk about drugs that are supposed to not act on his head.
painkillers
The first thing to say about non-prescription drugs. They are sold in any drugstore, and the names will not be asked.
Most people buy a nonsteroidal anti-inflammatory drugs such as ibuprofen or aspirin. In 1994 he conducted a study and found that these medications disrupt sleep. The mechanism of action of NSAIDs is associated with impaired synthesis of prostaglandins. It is believed that prostaglandins may be involved in the regulation of sleep. If you disrupt their production, then sleep disturbed.
Another anti-inflammatory drugs inhibit the nocturnal secretion of our inner hormone melatonin and hypnotic, maybe even from antipyretic body temperature decreases. All of this interferes with normal sleep and people often wake up.
Paracetamol, which is used as painkillers, does not affect sleep.
But the anti-inflammatory tablets will improve sleep to those people who have something hurts. So it's all relative.
Beta-blockers
These drugs decrease heart rate and decrease blood pressure. Beta-blockers are lipophilic and hydrophilic. Lipophilic (fat soluble) include propranolol (Inderal), metoprolol (Egilok, Betalok).
Fat-soluble drugs by their nature are capable to penetrate biological membranes. All these membranes are themselves composed of layers of fat-like molecules, so take fat-soluble medicines like family. That is why the lipophilic beta-blockers can penetrate the blood-brain barrier.
Normally, the blood-brain barrier separates our brain from anything that swims in blood. In the case of lipophilic beta-blockers barrier does not work, medicines penetrate into the brain and hosted there. From them, people often wake up at night. Another of them are nightmares and daytime sleepiness.
glucocorticoids
This anti-hormones that accept at different arthritis or asthma.
A huge number of people complaining about the fact that these drugs disrupt sleep. Here are just some reason in scientific research as long as this effect has not been confirmed.
In general, we doctors are wary of the first in the life of the patient appointment of glucocorticoids. There are situations when you need to immediately give a large dose of hormones. From this sometimes occurs in people mental disorder. So that the effect of glucocorticoids on sleep quite naturally.
I must say that most often used for asthma inhaled glucocorticoids nor sleep, nor the psyche is not affected.
theophylline
He is known as the teopeka. This medicine is used in bronchial asthma and other lung diseases.
When theophylline was studied on the subject of sleep deterioration, it was found that this drug at the same time improves nighttime sleep and daytime alertness increases. Alertness - the ability to stay calm and still be ready for action. That is such a discipline. The military is very welcome.
Theophylline belongs to the same group of compounds as caffeine. This, it seems, everything is explained.
Which of this we can conclude
Chances are any medications that penetrate the blood-brain barrier, may affect sleep. This is not always a bad thing, and it does not need to be frightened. It is better to know about it in advance and on occasion not to panic.
If you liked this article, then click the "thumbs up" and subscribe to my channel. Read my articles on related topics:
sleep hygiene
Four types of harmful drugs for the heart
A list of drugs that can ruin your eyesight
How to safely stop drinking hormones
