Intrahepatic cholestasis in pregnancy: Causes, Symptoms and Treatment

Sometimes during pregnancy women are red and itchy feet and hands, such symptoms may indicate a syndrome of intrahepatic cholestasis. Is it dangerous for pregnant and how to treat it?

Reasons why manifested cholestasis in pregnant women is still not fully understood. But there is speculation that its development is associated with genetics, in particular genetically determined hypersensitivity of the female body to estrogens. And because the content of estrogen in normal pregnancy increased almost 1,000 times, this factor leads to the development of cholestasis in some women, hatching baby.

Intrahepatic cholestasis affects the most sensitive to estrogen organ - the liver, due to the in disrupted bile production therein and its natural outflow decreases as the intestine, and in blood. Interestingly, the liver at the same time does not change either its size or consistency.

symptoms of cholestasis

The disease is manifested sufficiently benign and specifically - Skin itching, mild jaundice, changes in the color of urine and feces. The main manifestations of cholestasis in pregnant women appear in the III trimester and tested immediately after birth. A pregnant woman may experience nausea, weakness, loss of appetite and sometimes unpleasant or painful sensations in the right upper quadrant.

The main symptoms of cholestasis - a skin itching, mild jaundice, discoloration of urine and stool, nausea, weakness, loss of appetite, pain in the right upper quadrant.

Pass the symptoms of cholestasis in the same sequence as the beginning. After a short period after birth when the hormonal balance is beginning to recover, within a couple of days disappear itching and jaundice, and passes through one or two weeks.

It is important to know that in time establish the diagnosis is very important in this disease, as this insidious disease is dangerous for both the pregnant woman and to her fetus. The main task of the doctors in the treatment of cholestasis - prevention of missed abortion. The main cause stillbirths in this pathology is anoxia or due to damage to the placenta, or exposure to bile acids, which can penetrate the placenta.

Treatment of intrahepatic cholestasis in pregnancy

Despite the fact that the risk of stillbirth is large enough, doctors in most cases still take a wait and administered at the same time stimulating the delivery 35 to 38 a week. At the same time each week carry out a thorough examination of the pregnant with the relevant analyzes. Just pregnant prescribe medication, enabling improved functionality liver.

One of the main places in the treatment of cholestasis takes compliance with certain diets, in which the amount is strictly controlled consumed fat and dairy products, and also recommended to use a sufficient number of products containing protein.

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